
Elizabeth Blackburn
Who was Elizabeth Blackburn?
Nobel Prize-winning molecular biologist who discovered telomerase, the enzyme that protects chromosomes and plays a key role in aging and cancer.
Biographical data adapted from Wikipedia’s article on Elizabeth Blackburn (CC BY-SA 4.0).
Biography
Elizabeth Helen Blackburn was born on November 26, 1948, in Hobart, Tasmania, Australia. She studied at the University of Melbourne for her undergraduate degree, then went on to Darwin College, University of Cambridge, to earn her doctorate. She attended University High School for her earlier education, and while at university, lived at Janet Clarke Hall. Blackburn began her scientific career researching chromosomes, focusing on telomeres, which are protective DNA-protein structures at the ends of chromosomes. In 1984, she and Carol W. Greider discovered telomerase, the enzyme that replenishes telomeres. This important finding showed how cells keep chromosome integrity during division and gave new insights into cellular aging and cancer development. It changed the understanding of how cells age and die, opening new paths for research into age-related diseases and possible treatments. Blackburn worked at several top institutions before becoming president of the Salk Institute for Biological Studies. Besides her lab work, she was active in biomedical ethics, serving on the President's Council on Bioethics during the Bush administration until she was controversially dismissed in 2004, leading to 170 scientists signing an open letter of support for her. She received many awards for her work, including the 2009 Nobel Prize in Physiology or Medicine, which she shared with Carol W. Greider and Jack W. Szostak. This made her the first Australian woman to win a Nobel Prize, marking her as one of the most influential molecular biologists of her time.
Before Fame
Growing up in Tasmania during the 1950s and 1960s, Blackburn became interested in nature and science early on. Her journey into molecular biology was influenced by the fast-paced developments in biochemistry and genetics at the time when scientists were starting to unravel DNA structure and cellular processes at the molecular level. The discovery of DNA's double helix in 1953 and the breakthroughs that followed in genetic research provided an opportunity for young scientists like Blackburn to explore key questions about life at the cellular level. Her studies at the University of Melbourne and later at Cambridge placed her at the cutting edge of new molecular biology techniques, setting the stage for the groundbreaking research that would mark her career.
Key Achievements
- Co-discovered telomerase enzyme in 1984 with Carol W. Greider
- Won the 2009 Nobel Prize in Physiology or Medicine, becoming the first Australian woman Nobel laureate
- Served as president of the Salk Institute for Biological Studies
- Received the Albert Lasker Award for Basic Medical Research in 2006
- Advanced understanding of cellular aging and cancer through telomere research
Did You Know?
- 01.She was controversially dismissed from President Bush's Council on Bioethics in 2004, with critics claiming it was due to her support for embryonic stem cell research
- 02.Her telomerase research began with studying pond scum organisms called Tetrahymena, which have unusual chromosome structures
- 03.She became an American citizen while maintaining her Australian citizenship, making her an Australian-American dual citizen
- 04.The 170 scientists who signed the open letter supporting her dismissal included several Nobel laureates
- 05.Her work on telomeres has implications for understanding both cancer (where cells become immortal) and aging (where telomeres shorten over time)
Awards & Honors
| Award | Year | Details |
|---|---|---|
| Nobel Prize in Physiology or Medicine | 2009 | for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase |
| Albert Lasker Award for Basic Medical Research | 2006 | — |
| L'Oréal-UNESCO Award For Women in Science | 2008 | — |
| Benjamin Franklin Medal | 2005 | — |
| Harvey Prize | 1999 | — |
| Canada Gairdner International Award | 1998 | — |
| Paul Ehrlich and Ludwig Darmstaedter Prize | 2009 | — |
| Louisa Gross Horwitz Prize | 2007 | — |
| Victorian Honour Roll of Women | 2010 | — |
| Albany Medical Center Prize | 2008 | — |
| Alfred P. Sloan, Jr. Prize | 2001 | — |
| Dr A.H. Heineken Prize for Medicine | 2004 | — |
| Dickson Prize in Medicine | 2000 | — |
| Gruber Prize in Genetics | 2006 | — |
| Pearl Meister Greengard Prize | 2008 | — |
| Rosenstiel Award | 1998 | — |
| California Hall of Fame | 2011 | — |
| E. B. Wilson Medal | 2001 | — |
| Keio Medical Science Prize | 1999 | — |
| Meyenburg Prize | 2006 | — |
| Bristol-Myers Squibb Award for Distinguished Achievement in Cancer Research | 2003 | — |
| ASCB Public Service Award | 2004 | — |
| Grand Prix Charles-Leopold Mayer | 1998 | — |
| NAS Award in Molecular Biology | 1990 | — |
| Keith R. Porter Lecture | 1999 | — |
| WICB Senior Award | 2005 | — |
| Weizmann Women & Science Award | 2008 | — |
| Time 100 | 2007 | — |
| Robert J. and Claire Pasarow Foundation Award for Distinguished Contributions to Cancer Research | 2003 | — |
| Royal Medal | 2015 | — |
| Corresponding Member of the Australian Academy of Science | 2007 | — |
| Fellow of the Royal Society of New South Wales | — | — |
| Fellow of the American Academy of Arts and Sciences | — | — |
| honorary doctor of Harvard University | 2006 | — |
| honorary doctor of Brandeis University | — | — |
| Companion of the Order of Australia | 2010 | — |
| Vanderbilt Prize in Biomedical Science | 2007 | — |
| Distinguished Fellow of the Royal Society of New South Wales | 2017 | — |
| American Institute of Chemists Gold Medal | 2012 | — |
| Australia Prize | — | — |
| Great Immigrants Award | 2010 | — |
| Clarivate Citation Laureates | 2009 | — |
| AACR-G.H.A. Clowes Award for Outstanding Basic Cancer Research | 2000 | — |
| Alma Dea Morani Award | 2017 | — |
Nobel Prizes
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