HistoryData
August Krogh

August Krogh

18741949 Denmark
pedagoguephysicianphysiologistuniversity teacherzoologist

Who was August Krogh?

Danish physiologist who won the 1920 Nobel Prize in Physiology or Medicine for discovering the mechanism of regulation of capillaries in skeletal muscle. His research on how blood flow is controlled at the microscopic level revolutionized understanding of circulation and oxygen delivery to tissues.

Biographical data adapted from Wikipedia’s article on August Krogh (CC BY-SA 4.0).

Died
1949
Copenhagen
Nationality
Zodiac Sign
Scorpio

Biography

Schack August Steenberg Krogh was a Danish physiologist who made groundbreaking contributions to circulatory physiology. Born on November 15, 1874, in Grenaa, Denmark, Krogh became a leading medical researcher in the early 20th century. He started his education at Aarhus Katedralskole and continued his studies at the University of Copenhagen, where he spent most of his career.

Krogh was a professor of zoophysiology at the University of Copenhagen from 1916 to 1945 and became known as an authority in physiological research. His major contribution was discovering how capillaries in skeletal muscle are regulated, a study that won him the Nobel Prize in Physiology or Medicine in 1920. He was the first scientist to explain how blood flow in muscles and organs changes with physiological demands by the opening and closing of arterioles and capillaries, revolutionizing the understanding of circulation and oxygen delivery at a microscopic level.

In addition to his research on capillaries, Krogh made key discoveries in various areas of physiology. He developed Krogh's principle, which states that for studying many physiological issues, nature has provided an animal species ideal for investigation. This principle influenced how researchers chose experimental models.

Krogh's work extended beyond academic research into practical applications. He helped found what is now Novo Nordisk, showing his dedication to turning scientific discoveries into medical applications. Throughout his career, he received numerous international honors, such as the Croonian Medal and Lecture in 1940, the Baly Medal in 1945, and Foreign Membership of the Royal Society in 1937. He was awarded honorary doctorates from Harvard University, Oxford University, Edinburgh University, Oslo University, and Lund University. Krogh passed away on September 13, 1949, in Copenhagen, leaving a lasting impact on physiological science.

Before Fame

Growing up in late 19th-century Denmark, Krogh experienced a time when biological sciences were rapidly advancing. As modern physiology became a distinct field, breakthroughs in microscopy and experimental techniques were happening too, and these would be key to his future work.

He studied at Aarhus Katedralskole and then the University of Copenhagen, putting him at the forefront of new methods in physiological research. The University of Copenhagen was turning into a hub for new biological research, giving Krogh access to the latest equipment and methods that allowed him to closely study circulatory mechanisms at the cellular level.

Key Achievements

  • Discovered the mechanism of capillary regulation in skeletal muscle, earning the 1920 Nobel Prize in Physiology or Medicine
  • Developed Krogh's principle, a fundamental concept in comparative physiology
  • Served as professor of zoophysiology at University of Copenhagen for nearly three decades (1916-1945)
  • Co-founded what became Novo Nordisk, bridging scientific research with pharmaceutical innovation
  • Received numerous international honors including Foreign Member of the Royal Society and multiple honorary doctorates

Did You Know?

  • 01.Krogh's principle, which he developed, suggests that for every biological problem there exists an organism or biological preparation that is optimal for its solution
  • 02.He was one of the founding figures behind Novo Nordisk, which began as Nordisk Insulin Laboratory and became one of the world's largest pharmaceutical companies
  • 03.Krogh's research involved studying frogs' capillaries under microscopes, leading to his discovery of how capillaries open and close to regulate blood flow
  • 04.His wife Marie Krogh was also a physiologist who conducted important research on lung function and gas exchange
  • 05.Krogh's laboratory techniques for studying capillary function were so advanced that they remained standard methodology for decades after his initial discoveries

Family & Personal Life

SpouseMarie Krogh
ChildBodil Schmidt-Nielsen

Awards & Honors

AwardYearDetails
Nobel Prize in Physiology or Medicine1920for his discovery of the capillary motor regulating mechanism
Croonian Medal and Lecture1940
honorary doctor of Harvard University
Honorary doctor of the University of Oxford
honorary doctor of the University of Edinburgh
honorary doctorate of the University of Oslo
Foreign Member of the Royal Society1937
Baly Medal1945
honorary doctorate of Lund University
Silliman Memorial Lectures1922

Nobel Prizes