2025 Susumu Kitagawa Japan Japanfor the development of metal–organic frameworks
2025 Richard Robson Australia Australiafor the development of metal–organic frameworks
2025 Omar M. Yaghi United States United Statesfor the development of metal–organic frameworks
2024 David Baker United States United Statesfor computational protein design
2024 Demis Hassabis United Kingdom United Kingdomfor protein structure prediction
2024 John Jumper United States United Statesfor protein structure prediction
2023 Moungi Bawendi United States United Statesfor the discovery and synthesis of quantum dots
2023 Louis Brus United States United Statesfor the discovery and synthesis of quantum dots
2023 Aleksey Yekimov United States United Statesfor the discovery and synthesis of quantum dots
2022 Carolyn Bertozzi United States United Statesfor the development of click chemistry and bioorthogonal chemistry
2022 Morten Meldal Denmark Denmarkfor the development of click chemistry and bioorthogonal chemistry
2022 K. Barry Sharpless United States United Statesfor the development of click chemistry and bioorthogonal chemistry
2021 Benjamin List Germany Germanyfor the development of asymmetric organocatalysis
2021 David W.C. MacMillan United States United Statesfor the development of asymmetric organocatalysis
2020 Emmanuelle Charpentier France Francefor the development of a method for genome editing
2020 Jennifer A. Doudna United States United Statesfor the development of a method for genome editing
2019 John B. Goodenough United States United Statesfor the development of lithium-ion batteries
2019 M. Stanley Whittingham United States United Statesfor the development of lithium-ion batteries
2019 Akira Yoshino Japan Japanfor the development of lithium-ion batteries
2018 Frances H. Arnold United States United Statesfor the directed evolution of enzymes
2018 George P. Smith United States United Statesfor the phage display of peptides and antibodies
2018 Sir Gregory P. Winter United Kingdom United Kingdomfor the phage display of peptides and antibodies
2017 Jacques Dubochet Switzerland Switzerlandfor developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution
2017 Joachim Frank United States United Statesfor developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution
2017 Richard Henderson United Kingdom United Kingdomfor developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution
2016 Jean-Pierre Sauvage France Francefor the design and synthesis of molecular machines
2016 Sir J. Fraser Stoddart United States United Statesfor the design and synthesis of molecular machines
2016 Ben Feringa Netherlands Netherlandsfor the design and synthesis of molecular machines
2015 Tomas Lindahl Sweden Swedenfor mechanistic studies of DNA repair
2015 Paul Modrich United States United Statesfor mechanistic studies of DNA repair
2015 Aziz Sancar Turkey Turkeyfor mechanistic studies of DNA repair
2014 Eric Betzig United States United Statesfor the development of super-resolved fluorescence microscopy
2014 Stefan Hell Germany Germanyfor the development of super-resolved fluorescence microscopy
2014 William E. Moerner United States United Statesfor the development of super-resolved fluorescence microscopy
2013 Martin Karplus United States United Statesfor the development of multiscale models for complex chemical systems
2013 Michael Levitt Israel Israelfor the development of multiscale models for complex chemical systems
2013 Arieh Warshel United States United Statesfor the development of multiscale models for complex chemical systems
2012 Robert J. Lefkowitz United States United Statesfor studies of G-protein-coupled receptors
2012 Brian Kobilka United States United Statesfor studies of G-protein-coupled receptors
2011 Dan Shechtman United States United Statesfor the discovery of quasicrystals
2010 Richard F. Heck United States United Statesfor palladium-catalyzed cross couplings in organic synthesis
2010 Ei-ichi Negishi Japan Japanfor palladium-catalyzed cross couplings in organic synthesis
2010 Akira Suzuki Japan Japanfor palladium-catalyzed cross couplings in organic synthesis
2009 Venkatraman Ramakrishnan United States United Statesfor studies of the structure and function of the ribosome
2009 Thomas A. Steitz United States United Statesfor studies of the structure and function of the ribosome
2009 Ada Yonath Israel Israelfor studies of the structure and function of the ribosome
2008 Osamu Shimomura Japan Japanfor the discovery and development of the green fluorescent protein, GFP
2008 Martin Chalfie United States United Statesfor the discovery and development of the green fluorescent protein, GFP
2008 Roger Y. Tsien United States United Statesfor the discovery and development of the green fluorescent protein, GFP
2007 Gerhard Ertl Germany Germanyfor his studies of chemical processes on solid surfaces
2006 Roger D. Kornberg United States United Statesfor his studies of the molecular basis of eukaryotic transcription
2005 Yves Chauvin France Francefor the development of the metathesis method in organic synthesis
2005 Robert H. Grubbs United States United Statesfor the development of the metathesis method in organic synthesis
2005 Richard R. Schrock United States United Statesfor the development of the metathesis method in organic synthesis
2004 Irwin Rose United States United Statesfor the discovery of ubiquitin-mediated protein degradation
2004 Aaron Ciechanover Israel Israelfor the discovery of ubiquitin-mediated protein degradation
2004 Avram Hershko Israel Israelfor the discovery of ubiquitin-mediated protein degradation
2003 Peter Agre United States United Statesfor the discovery of water channels
2003 Roderick MacKinnon United States United Statesfor structural and mechanistic studies of ion channels
2002 John B. Fenn United States United Statesfor their development of soft desorption ionisation methods for mass spectrometric analyses of biological macromolecules
2002 Koichi Tanaka Japan Japanfor their development of soft desorption ionisation methods for mass spectrometric analyses of biological macromolecules
2002 Kurt Wüthrich Switzerland Switzerlandfor his development of nuclear magnetic resonance spectroscopy for determining the three-dimensional structure of biological macromolecules in solution
2001 William Knowles United States United Statesfor their work on chirally catalysed hydrogenation reactions
2001 Ryōji Noyori Japan Japanfor their work on chirally catalysed hydrogenation reactions
2001 K. Barry Sharpless United States United Statesfor his work on chirally catalysed oxidation reactions
2000 Alan Heeger United States United Statesfor the discovery and development of conductive polymers
2000 Alan MacDiarmid United States United Statesfor the discovery and development of conductive polymers
2000 Hideki Shirakawa Japan Japanfor the discovery and development of conductive polymers
1999 Ahmed Zewail United States United Statesfor his studies of the transition states of chemical reactions using femtosecond spectroscopy
1998 Walter Kohn United States United Statesfor his development of the density-functional theory
1998 John Pople United Kingdom United Kingdomfor his development of computational methods in quantum chemistry
1997 Paul D. Boyer United States United Statesfor their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP)
1997 John E. Walker United Kingdom United Kingdomfor their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP)
1997 Jens Christian Skou Denmark Denmarkfor the first discovery of an ion-transporting enzyme, Na+, K+ -ATPase
1996 Robert F. Curl Jr. United States United Statesfor their discovery of fullerenes
1996 Sir Harold Kroto United Kingdom United Kingdomfor their discovery of fullerenes
1996 Richard E. Smalley United States United Statesfor their discovery of fullerenes
1995 Paul Josef Crutzen Germany Germanyfor their work in atmospheric chemistry, particularly concerning the formation and decomposition of ozone
1995 Mario Molina United States United Statesfor their work in atmospheric chemistry, particularly concerning the formation and decomposition of ozone
1995 F. Sherwood Rowland United States United Statesfor their work in atmospheric chemistry, particularly concerning the formation and decomposition of ozone
1994 George A. Olah United States United Statesfor his contribution to carbocation chemistry
1993 Kary B. Mullis United States United Statesfor his invention of the polymerase chain reaction (PCR) method
1993 Michael Smith Canada Canadafor his fundamental contributions to the establishment of oligonucleotide-based, site-directed mutagenesis and its development for protein studies
1992 Rudolph A. Marcus United States United Statesfor his contributions to the theory of electron transfer reactions in chemical systems
1991 Richard R. Ernst Switzerland Switzerlandfor his contributions to the development of the methodology of high resolution nuclear magnetic resonance (NMR) spectroscopy
1990 Elias James Corey United States United Statesfor his development of the theory and methodology of organic synthesis
1989 Sidney Altman United States United Statesfor their discovery of catalytic properties of RNA
1989 Thomas R. Cech United States United Statesfor their discovery of catalytic properties of RNA
1988 Johann Deisenhofer United States United Statesfor the determination of the three-dimensional structure of a photosynthetic reaction centre
1988 Robert Huber Germany Germanyfor the determination of the three-dimensional structure of a photosynthetic reaction centre
1988 Hartmut Michel Germany Germanyfor the determination of the three-dimensional structure of a photosynthetic reaction centre
1987 Donald J. Cram United States United Statesfor their development and use of molecules with structure-specific interactions of high selectivity
1987 Jean-Marie Lehn France Francefor their development and use of molecules with structure-specific interactions of high selectivity
1987 Charles J. Pedersen United States United Statesfor their development and use of molecules with structure-specific interactions of high selectivity
1986 Dudley R. Herschbach United States United Statesfor their contributions concerning the dynamics of chemical elementary processes
1986 Yuan T. Lee Taiwan Taiwanfor their contributions concerning the dynamics of chemical elementary processes
1986 John C. Polanyi Canada Canadafor their contributions concerning the dynamics of chemical elementary processes
1985 Herbert A. Hauptman United States United Statesfor their outstanding achievements in the development of direct methods for the determination of crystal structures
1985 Jerome Karle United States United Statesfor their outstanding achievements in the development of direct methods for the determination of crystal structures
1984 Bruce Merrifield United States United Statesfor his development of methodology for chemical synthesis on a solid matrix
1983 Henry Taube United States United Statesfor his work on the mechanisms of electron transfer reactions, especially in metal complexes
1982 Aaron Klug United Kingdom United Kingdomfor his development of crystallographic electron microscopy and his structural elucidation of biologically important nucleic acid-protein complexes
1981 Kenichi Fukui Japan Japanfor their theories, developed independently, concerning the course of chemical reactions
1981 Roald Hoffmann Poland Polandfor their theories, developed independently, concerning the course of chemical reactions
1980 Paul Berg United States United Statesfor his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA
1980 Walter Gilbert United States United Statesfor their contributions concerning the determination of base sequences in nucleic acids
1980 Frederick Sanger United Kingdom United Kingdomfor their contributions concerning the determination of base sequences in nucleic acids
1979 Herbert C. Brown United States United Statesfor their development of the use of boron- and phosphorus-containing compounds, respectively, into important reagents in organic synthesis
1979 Georg Wittig Germany Germanyfor their development of the use of boron- and phosphorus-containing compounds, respectively, into important reagents in organic synthesis
1978 Peter D. Mitchell United Kingdom United Kingdomfor his contribution to the understanding of biological energy transfer through the formulation of the chemiosmotic theory
1977 Ilya Prigogine Belgium Belgiumfor his contributions to non-equilibrium thermodynamics, particularly the theory of dissipative structures
1976 William Lipscomb United States United Statesfor his studies on the structure of boranes illuminating problems of chemical bonding
1975 John Cornforth Australia Australiafor his work on the stereochemistry of enzyme-catalyzed reactions
1975 Vladimir Prelog Serbia Serbiafor his research into the stereochemistry of organic molecules and reactions
1974 Paul J. Flory United States United Statesfor his fundamental achievements, both theoretical and experimental, in the physical chemistry of the macromolecules
1973 Ernst Otto Fischer Germany Germanyfor their pioneering work, performed independently, on the chemistry of the organometallic, so called sandwich compounds
1973 Geoffrey Wilkinson United Kingdom United Kingdomfor their pioneering work, performed independently, on the chemistry of the organometallic, so called sandwich compounds
1972 Christian Anfinsen United States United Statesfor his work on ribonuclease, especially concerning the connection between the amino acid sequence and the biologically active conformation
1972 Stanford Moore United States United Statesfor their contribution to the understanding of the connection between chemical structure and catalytic activity of the active centre of the ribonuclease molecule
1972 William H. Stein United States United Statesfor their contribution to the understanding of the connection between chemical structure and catalytic activity of the active centre of the ribonuclease molecule
1971 Gerhard Herzberg Canada Canadafor his contributions to the knowledge of electronic structure and geometry of molecules, particularly free radicals
1970 Luis Leloir Argentina Argentinafor his discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates
1969 Derek Barton United Kingdom United Kingdomfor their contributions to the development of the concept of conformation and its application in chemistry
1969 Odd Hassel Norway Norwayfor their contributions to the development of the concept of conformation and its application in chemistry
1968 Lars Onsager United States United Statesfor the discovery of the reciprocal relations bearing his name, which are fundamental for the thermodynamics of irreversible processes
1967 Manfred Eigen Germany Germanyfor their studies of extremely fast chemical reactions, effected by disturbing the equilibrium by means of very short pulses of energy
1967 Ronald G.W. Norrish United Kingdom United Kingdomfor their studies of extremely fast chemical reactions, effected by disturbing the equilibrium by means of very short pulses of energy
1967 George Porter United Kingdom United Kingdomfor their studies of extremely fast chemical reactions, effected by disturbing the equilibrium by means of very short pulses of energy
1966 Robert S. Mulliken United States United Statesfor his fundamental work concerning chemical bonds and the electronic structure of molecules by the molecular orbital method
1965 Robert B. Woodward United States United Statesfor his outstanding achievements in the art of organic synthesis
1964 Dorothy Hodgkin United Kingdom United Kingdomfor her determinations by X-ray techniques of the structures of important biochemical substances
1963 Karl Ziegler Germany Germanyfor their discoveries in the field of the chemistry and technology of high polymers
1963 Giulio Natta Italy Italyfor their discoveries in the field of the chemistry and technology of high polymers
1962 Max F. Perutz United Kingdom United Kingdomfor their studies of the structures of globular proteins
1962 John C. Kendrew United Kingdom United Kingdomfor their studies of the structures of globular proteins
1961 Melvin Calvin United States United Statesfor his research on the carbon dioxide assimilation in plants
1960 Willard F. Libby United States United Statesfor his method to use carbon-14 for age determination in archaeology, geology, geophysics, and other branches of science
1959 Jaroslav Heyrovsky Czech Republic Czech Republicfor his discovery and development of the polarographic methods of analysis
1958 Frederick Sanger United Kingdom United Kingdomfor his work on the structure of proteins, especially that of insulin
1957 Lord Todd United Kingdom United Kingdomfor his work on nucleotides and nucleotide co-enzymes
1956 Sir Cyril Hinshelwood United Kingdom United Kingdomfor their researches into the mechanism of chemical reactions
1956 Nikolay Semenov Russia Russiafor their researches into the mechanism of chemical reactions
1955 Vincent du Vigneaud United States United Statesfor his work on biochemically important sulphur compounds, especially for the first synthesis of a polypeptide hormone
1954 Linus Pauling United States United Statesfor his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances
1953 Hermann Staudinger Germany Germanyfor his discoveries in the field of macromolecular chemistry
1952 Archer John Porter Martin United Kingdom United Kingdomfor their invention of partition chromatography
1952 Richard L.M. Synge United Kingdom United Kingdomfor their invention of partition chromatography
1951 Edwin M. McMillan United States United Statesfor their discoveries in the chemistry of the transuranium elements
1951 Glenn T. Seaborg United States United Statesfor their discoveries in the chemistry of the transuranium elements
1950 Otto Diels Germany Germanyfor their discovery and development of the diene synthesis
1950 Kurt Alder Germany Germanyfor their discovery and development of the diene synthesis
1949 William Giauque United States United Statesfor his contributions in the field of chemical thermodynamics, particularly concerning the behaviour of substances at extremely low temperatures
1948 Arne Tiselius Sweden Swedenfor his research on electrophoresis and adsorption analysis, especially for his discoveries concerning the complex nature of the serum proteins
1947 Sir Robert Robinson United Kingdom United Kingdomfor his investigations on plant products of biological importance, especially the alkaloids
1946 James B. Sumner United States United Statesfor his discovery that enzymes can be crystallized
1946 John H. Northrop United States United Statesfor their preparation of enzymes and virus proteins in a pure form
1946 Wendell M. Stanley United States United Statesfor their preparation of enzymes and virus proteins in a pure form
1945 Artturi Ilmari Virtanen Finland Finlandfor his research and inventions in agricultural and nutrition chemistry, especially for his fodder preservation method
1944 Otto Hahn Germany Germanyfor his discovery of the fission of heavy nuclei
1943 George de Hevesy Sweden Swedenfor his work on the use of isotopes as tracers in the study of chemical processes
1939 Adolf Butenandt Germany Germanyfor his work on sex hormones
1939 Leopold Ruzicka Austria Austriafor his work on polymethylenes and higher terpenes
1938 Richard Kuhn Germany Germanyfor his work on carotenoids and vitamins
1937 Norman Haworth United Kingdom United Kingdomfor his investigations on carbohydrates and vitamin C
1937 Paul Karrer Switzerland Switzerlandfor his investigations on carotenoids, flavins and vitamins A and B2
1936 Peter Debye United States United Statesfor his contributions to our knowledge of molecular structure through his investigations on dipole moments and on the diffraction of X-rays and electrons in gases
1935 Frédéric Joliot-Curie France Francein recognition of their synthesis of new radioactive elements
1935 Irène Joliot-Curie France Francein recognition of their synthesis of new radioactive elements
1934 Harold C. Urey United States United Statesfor his discovery of heavy hydrogen
1932 Irving Langmuir United States United Statesfor his discoveries and investigations in surface chemistry
1931 Carl Bosch Germany Germanyin recognition of their contributions to the invention and development of chemical high pressure methods
1931 Friedrich Bergius Germany Germanyin recognition of their contributions to the invention and development of chemical high pressure methods
1930 Hans Fischer Germany Germanyfor his researches into the constitution of haemin and chlorophyll and especially for his synthesis of haemin
1929 Arthur Harden United Kingdom United Kingdomfor their investigations on the fermentation of sugar and fermentative enzymes
1929 Hans von Euler-Chelpin Sweden Swedenfor their investigations on the fermentation of sugar and fermentative enzymes
1928 Adolf Windaus Germany Germanyfor the services rendered through his research into the constitution of the sterols and their connection with the vitamins
1927 Heinrich Wieland Germany Germanyfor his investigations of the constitution of the bile acids and related substances
1926 Theodor Svedberg Sweden Swedenfor his work on disperse systems
1925 Richard Zsigmondy Austria Austriafor his demonstration of the heterogenous nature of colloid solutions and for the methods he used, which have since become fundamental in modern colloid chemistry
1923 Fritz Pregl Serbia Serbiafor his invention of the method of micro-analysis of organic substances
1922 Francis W. Aston United Kingdom United Kingdomfor his discovery, by means of his mass spectrograph, of isotopes, in a large number of non-radioactive elements, and for his enunciation of the whole-number rule
1921 Frederick Soddy United Kingdom United Kingdomfor his contributions to our knowledge of the chemistry of radioactive substances, and his investigations into the origin and nature of isotopes
1920 Walther Nernst Germany Germanyin recognition of his work in thermochemistry
1918 Fritz Haber Germany Germanyfor the synthesis of ammonia from its elements
1915 Richard Willstätter Germany Germanyfor his researches on plant pigments, especially chlorophyll
1914 Theodore W. Richards United States United Statesin recognition of his accurate determinations of the atomic weight of a large number of chemical elements
1913 Alfred Werner Switzerland Switzerlandin recognition of his work on the linkage of atoms in molecules by which he has thrown new light on earlier investigations and opened up new fields of research especially in inorganic chemistry
1912 Victor Grignard France Francefor the discovery of the so-called Grignard reagent, which in recent years has greatly advanced the progress of organic chemistry
1912 Paul Sabatier France Francefor his method of hydrogenating organic compounds in the presence of finely disintegrated metals whereby the progress of organic chemistry has been greatly advanced in recent years
1911 Marie Curie Russia Russiain recognition of her services to the advancement of chemistry by the discovery of the elements radium and polonium, by the isolation of radium and the study of the nature and compounds of this remarkable element
1910 Otto Wallach Germany Germanyin recognition of his services to organic chemistry and the chemical industry by his pioneer work in the field of alicyclic compounds
1909 Wilhelm Ostwald Germany Germanyin recognition of his work on catalysis and for his investigations into the fundamental principles governing chemical equilibria and rates of reaction
1908 Ernest Rutherford New Zealand New Zealandfor his investigations into the disintegration of the elements, and the chemistry of radioactive substances
1907 Eduard Buchner Germany Germanyfor his biochemical researches and his discovery of cell-free fermentation
1906 Henri Moissan France Francein recognition of the great services rendered by him in his investigation and isolation of the element fluorine, and for the adoption in the service of science of the electric furnace called after him
1905 Adolf von Baeyer Germany Germanyin recognition of his services in the advancement of organic chemistry and the chemical industry, through his work on organic dyes and hydroaromatic compounds
1904 Sir William Ramsay United Kingdom United Kingdomin recognition of his services in the discovery of the inert gaseous elements in air, and his determination of their place in the periodic system
1903 Svante August Arrhenius Sweden Swedenin recognition of the extraordinary services he has rendered to the advancement of chemistry by his electrolytic theory of dissociation
1902 Emil Fischer Germany Germanyin recognition of the extraordinary services he has rendered by his work on sugar and purine syntheses
1901 Jacobus Henricus van 't Hoff Netherlands Netherlandsin recognition of the extraordinary services he has rendered by the discovery of the laws of chemical dynamics and osmotic pressure in solutions